Aiming at the target: improved adjuvant medical therapy

Chronic lymphocytic leukemia--aiming at a moving target!

Forecasting changes in amphibian biodiversity: aiming at a moving target.

Amphibian population declines and sudden species' extinctions began to be noted at the beginning of the 1980s. Understanding the causes of the losses is hampered by our poor knowledge of the amphibian fauna in many parts of the world. Amphibian taxa are still being described at a high rate, especially in the tropics, which means that even quantifying species lost as a percentage of the current ...

Fifty years of interferon research: aiming at a moving target.

Nearly half a century has passed since the first published description of interferons (IFNs). This commentary introduces the four accompanying review articles on type I IFN research and attempts to relate how the field of IFN research has been changing during its history.

Aiming at a Moving Target: IT Alignment in Toy Companies

For global companies that compete in high-velocity industries, business strategies and initiatives change rapidly, and thus the CIO struggles to keep the IT organization aligned with a moving target. In this paper we report on research-in-progress that focuses on how the CIO attempts to meet this challenge. Specifically, we are conducting case studies to closely examine how toy industry CIOs de...

Nanoelectronics aiming at cancer.

Featured Article: Zheng GF, Patolsky F, Cui Y, Wang WU, Lieber CM. Multiplexed electrical detection of cancer markers with nanowire sensor arrays. Nat Biotechnol 2005;23:1294–301. There are 200 types of cancers, each with many variants. The devastating effects of cancer on patients and their families extract a huge loss. For instance, nearly 1.5 million people in the US alone are diagnosed with...